The NSU RO 80 was a technologically advanced, large sedan-type automobile produced by the German firm NSU from 1967–1977 with a production of 37,204 vehicles. Most notable was the powertrain: 113 bhp, 995 cc twin rotor Wankel engine driving the front wheels through a semi-automatic transmission employing an innovative vacuum system. It was voted Car of the Year in 1968 by European automotive writers.

The styling by Claus Luthe, who was head of design at NSU and later BMW, was considered very modern at the time and still holds up well; the Ro 80 has been part of many gallery exhibits of modern industrial design.

Surviving NSU’s are now considered highly prized classic cars with values to match.